It's not even out yet, but I've received another great response to the The Passage by Justin Cronin (early June 2010 release).
Remember it's post-apocalyptic, involves vampires and is (as the publisher Random House notes) "a relentlessly suspenseful adventure and an epic chronicle of human endurance in the face of unprecedented catastrophe and unimaginable danger."
Reader feedback: "I really enjoyed the book. It had quite a few "twists and turns" and held my attention throughout. Towards the end, there were a few good surprises as well. When I think about it, it kind of reminds me of the Lord of the Rings: a band of characters on a quest with plenty of dangers on the way...Watch out for any guy named Babcock!"
When you read the book, you'll know why you don't want Babcock to show up on your doorstep.